The sterol response element binding protein regulates cyclooxygenase-2 gene expression in endothelial cells
We previously demonstrated that cholesterol deprivation increases endothelial cyclooxygenase-2 (COX-2)-dependent prostacyclin [prostaglandin I2 (PGI2)] production in vitro.Cholesterol directly regulates gene royal blue iphone 14 case transcription through the sterol response element binding protein (SREBP).In this work, we demonstrate that SREBP di